Information on Retin-A

Retin-A is a prescription cream medication that is used to effectively treat acne.

How does Retin-A work?

Retin-A acts primarily by modifying the abnormal keratinization (formation of the superficial layer of skin) located around hair follicles. Comedones (large deep seeded pus filled pimples) form in follicles with an excess of keratinized superficial skin cells. Retin-A promotes the detachment of these excess cells and the enhanced shedding of these cells from the follicular base. The contents are emptied and the formation of new comedones is significantly reduced.

How effective is Retin-A?

In a number of different clinical studies Retin-A was significantly superior to a placebo gel in decreasing comedo count. Approximately 25% of patients achieved superior results with the use of this medication.

How to apply Retin-A:

Apply a thin layer to affected areas at bedtime. Use a gauze pad or cotton swab to apply the liquid. Wash your hands immediately after use. Using this medication more frequently or in excessive amounts does not improve the results, but may increase side effects. Avoid applying near the eyes, mouth, or open cuts since this medication can irritate sensitive skin. Acne may appear to worsen when the medication is first used; continue therapy. It may take three to six weeks before the full benefits of this medication are seen.

Side Effects:

Immediately after applying, your skin may feel warm or mild stinging or minor redness may occur. Some peeling of the skin may occur. These effects should subside as your skin adjusts to the medication. If they persist or become bothersome, stop the medication and consult your doctor. This medicine may also increase sun sensitivity. Retin-A may also cause itchiness and scaling of the skin. This can sometimes be very extreme depending on the individual. Most people will experience some itching or scaling if too much Retin-A is applied.

Cautions:

Retin-A can increase sensitivity to sunlight, wind and cold. Avoid prolonged exposure to the sun and sunlamps. Wear protective clothing and use an effective sunscreen. It should be used during pregnancy only if clearly needed. It is not known if Retin-A appears in breast milk. Consult your doctor before breast-feeding. Use mild soap when washing your face. Do not wash face excessively. Abrasive soaps, cleansers, medicated creams or lotions can increase skin irritation.